Apheresis Stem Cell Collection
Estimate collection target yield, back-calculate collection efficiency, and review a yield table across CE and processed TBV values.
Project CD34 yield from donor TBV and CE
Donor TBV uses Nadler constants
Gender
M
Constant 1
0.37
Constant 2
0.03
Constant 3
0.6
CD34 yield
3.43 x 10e6/kg
Processed TBV
3.95x
Formula: CE x Peripheral CD34 x Processed blood / Recipient weight = (30 / 100) x 40 x 20 / 70 = 3.43 x 10e6/kg
Back-calculate CE from actual product values
CD34 yield
3.57 x 10e6/kg
CD34 yield = Product CD34 x Product volume / Recipient weight. CE then back-calculates from yield, peripheral CD34, and processed blood volume.
Projected CD34 yield table
The table uses the current donor TBV, peripheral CD34+, and recipient weight from the collection target calculator, then projects CD34 yield across a range of collection efficiencies and processed total blood volumes.
Based on donor TBV 5.06 L
| CE | TBV | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| % | 1 | 1.5 | 2 | 2.5 | 3 | 3.5 | 4 | 4.5 | 5 | 5.5 | 6 |
| 10 | 0.3 | 0.4 | 0.6 | 0.7 | 0.9 | 1 | 1.2 | 1.3 | 1.4 | 1.6 | 1.7 |
| 15 | 0.4 | 0.7 | 0.9 | 1.1 | 1.3 | 1.5 | 1.7 | 2 | 2.2 | 2.4 | 2.6 |
| 20 | 0.6 | 0.9 | 1.2 | 1.4 | 1.7 | 2 | 2.3 | 2.6 | 2.9 | 3.2 | 3.5 |
| 25 | 0.7 | 1.1 | 1.4 | 1.8 | 2.2 | 2.5 | 2.9 | 3.3 | 3.6 | 4 | 4.3 |
| 30 | 0.9 | 1.3 | 1.7 | 2.2 | 2.6 | 3 | 3.5 | 3.9 | 4.3 | 4.8 | 5.2 |
| 35 | 1 | 1.5 | 2 | 2.5 | 3 | 3.5 | 4 | 4.6 | 5.1 | 5.6 | 6.1 |
| 40 | 1.2 | 1.7 | 2.3 | 2.9 | 3.5 | 4 | 4.6 | 5.2 | 5.8 | 6.4 | 6.9 |
| 45 | 1.3 | 2 | 2.6 | 3.3 | 3.9 | 4.6 | 5.2 | 5.9 | 6.5 | 7.2 | 7.8 |
| 50 | 1.4 | 2.2 | 2.9 | 3.6 | 4.3 | 5.1 | 5.8 | 6.5 | 7.2 | 8 | 8.7 |